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  • Anti-KRT18 Polyclonal Antibody
  • Anti-KRT18 Polyclonal Antibody
產品名稱:

Anti-KRT18 Polyclonal Antibody

產品品牌: SOLARBIO/索萊寶 價格:
廠商性質: 生產廠家 產品時間: 2022-08-15
Anti-KRT18 Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應Human Mouse Rat

產品概述

品牌SOLARBIO/索萊寶貨號K106590P
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB IHC應用領域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產業(yè),農林牧漁

Anti-KRT18 Polyclonal Antibody

英文名稱Anti-KRT18 Polyclonal Antibody
宿主Rabbit
別名CK-18;CYK18;K18;PIG46;Cytokeratin-18
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:50-200.
交叉反應Human Mouse Rat
蛋白分子量26kDa
Gene ID3875
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human KRT18
性狀液體
Public Immunogen RangeRecombinant protein of human KRT18
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP05783
克隆類型Polyclonal Antibody
背景資料KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

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