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當(dāng)前位置：首頁(yè)產(chǎn)品中心免疫學(xué)K200045MAnti-NFKB p65 Monoclonal Antibody

Anti-NFKB p65 Monoclonal Antibody
產(chǎn)品簡(jiǎn)介：

Anti-NFKB p65 Monoclonal Antibody
應(yīng)用 WB IHC IP
稀釋比例WB 1:1000-3000. IP 1:100-300. IF 1:100-200. IHC 1:200-500.
交叉反應(yīng) Human Mouse Rat

產(chǎn)品型號(hào)：K200045M

更新時(shí)間：2022-08-15

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產(chǎn)品介紹

Anti-NFKB p65 Monoclonal Antibody

英文名稱Anti-NFKB p65 Monoclonal Antibody
宿主Mouse
別名MGC131774;NFKB 3;NFKB3;TF65_HUMAN
應(yīng)用WB IHC IP
稀釋比例WB 1:1000-3000. IP 1:100-300. IF 1:100-200. IHC 1:200-500.
蛋白分子量65kDa
Gene ID5970
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG1
免疫原recombinant protein
性狀液體
Public Immunogen Range

recombinant protein

Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ04206
克隆號(hào)5G6
克隆類型Monoclonal Antibody
背景資料NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.

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